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Anti-TIF1γ Dermatomyositis with Scleroderma-Like Pattern

Name: Anti-TIF1γ Dermatomyositis with Scleroderma-Like Pattern
Creator: Franklin Uguña Sari

Dermatomyositis (anti-TIF1γ+) Scleroderma-Like Pattern Severe

A 67-year-old man with chronic anti-TIF1γ-positive dermatomyositis and a scleroderma-like capillaroscopy pattern.

Author Franklin Uguña Sari

Clinical context

Two-year history of V-neck lesions and hypomyopathic weakness on chronic low-dose methotrexate and prednisone.

Capillaroscopy

Capillaroscopy shows severely reduced capillary density (2.7/mm), architectural disorganization, frequent dilations, giant capillaries, and abnormal/ramified forms (2/3 on the semi-quantitative scale), consistent with a scleroderma-like pattern.

Key Capillaroscopic Findings

Severe capillary loss (2.7/mm)
Giant capillaries (36.7%) and frequent dilations (41.1%)
Abnormal or ramified capillaries (37.8%)
Architectural disorganization

Anti-TIF1γ Dermatomyositis with Scleroderma-Like Pattern

Clinical images

Skin lesions in V-neck distribution