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MPO-ANCA Vasculitis with Rapidly Progressive Glomerulonephritis

ANCA-Associated Vasculitis (MPO+) Non-Specific Pattern Moderate

A 57-year-old man with newly diagnosed MPO-ANCA vasculitis and rapidly progressive glomerulonephritis.

Author Gema María Lledó Ibáñez

Clinical context

The patient presented with renal failure and nephritic syndrome, and kidney biopsy confirmed rapidly progressive glomerulonephritis in the setting of MPO-ANCA vasculitis.

Capillaroscopy

Capillaroscopy shows mildly reduced density (7.0 capillaries/mm), frequent capillary dilations, hemorrhages, and no giant capillaries, consistent with a non-specific microvascular pattern.

Key Capillaroscopic Findings

Mild capillary density reduction (7.0/mm)
Frequent capillary dilations (58.2%)
Hemorrhages (0.5/mm), without giant capillaries